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Mechanisms of EGFR-TKI-Induced Apoptosis and Strategies Targeting Apoptosis in EGFR-Mutated Non-Small Cell Lung Cancer

Homeostasis is achieved by balancing cell survival and death. In cancer cells, especially those carrying driver mutations, the processes and signals that promote apoptosis are inhibited, facilitating the survival and proliferation of these dysregulated cells. Apoptosis induction is an important mech...

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Detalles Bibliográficos
Autores principales: Nishihara, Shigetoshi, Yamaoka, Toshimitsu, Ishikawa, Fumihiro, Higuchi, Kensuke, Hasebe, Yuki, Manabe, Ryo, Kishino, Yasunari, Kusumoto, Sojiro, Ando, Koichi, Kuroda, Yusuke, Ohmori, Tohru, Sagara, Hironori, Yoshida, Hitoshi, Tsurutani, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778480/
https://www.ncbi.nlm.nih.gov/pubmed/36553449
http://dx.doi.org/10.3390/genes13122183