The Identification of Large Rearrangements Involving Intron 2 of the CDH1 Gene in BRCA1/2 Negative and Breast Cancer Susceptibility

E-cadherin, a CDH1 gene product, is a calcium-dependent cell–cell adhesion molecule playing a critical role in the establishment of epithelial architecture, maintenance of cell polarity, and differentiation. Germline pathogenic variants in the CDH1 gene are associated with hereditary diffuse gastric...

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Detalles Bibliográficos
Autores principales: Ben Aissa-Haj, Jihenne, Pinheiro, Hugo, Cornelis, François, Sebai, Molka, Meseure, Didier, Briaux, Adrien, Berteaux, Philippe, Lefol, Cedric, Des Guetz, Gaëtan, Trassard, Martine, Stevens, Denise, Vialard, François, Bieche, Ivan, Noguès, Catherine, Tang, Roseline, Oliveira, Carla, Stoppat-Lyonnet, Dominique, Lidereau, Rosette, Rouleau, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778491/
https://www.ncbi.nlm.nih.gov/pubmed/36553480
http://dx.doi.org/10.3390/genes13122213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778491/
https://www.ncbi.nlm.nih.gov/pubmed/36553480
http://dx.doi.org/10.3390/genes13122213

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