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Activation Mechanism of RhoA Caused by Constitutively Activating Mutations G14V and Q63L

RhoA, a member of Rho GTPases, regulates myriad cellular processes. Abnormal expression of RhoA has been implicated in various diseases, including cancers, developmental disorders and bacterial infections. RhoA mutations G14V and Q63L have been reported to constitutively activate RhoA. To figure out...

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Detalles Bibliográficos
Autores principales: Chen, Shiyao, Zhang, Zirui, Zhang, Yijing, Choi, Taeyoung, Zhao, Yaxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778661/
https://www.ncbi.nlm.nih.gov/pubmed/36555100
http://dx.doi.org/10.3390/ijms232415458