LMNA Co-Regulated Gene Expression as a Suitable Readout after Precise Gene Correction

LMNA-related muscular dystrophy is an autosomal-dominant progressive disorder caused by mutations in LMNA. LMNA missense mutations are becoming correctable with CRISPR/Cas9-derived tools. Evaluating the functional recovery of LMNA after gene editing bears challenges as there is no reported direct lo...

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Detalles Bibliográficos
Autores principales: Wang, Haicui, Krause, Anne, Escobar, Helena, Müthel, Stefanie, Metzler, Eric, Spuler, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778678/
https://www.ncbi.nlm.nih.gov/pubmed/36555163
http://dx.doi.org/10.3390/ijms232415525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778678/
https://www.ncbi.nlm.nih.gov/pubmed/36555163
http://dx.doi.org/10.3390/ijms232415525

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