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Rat Hepatocytes Mitigate Cadmium Toxicity by Forming Annular Gap Junctions and Degrading Them via Endosome–Lysosome Pathway

Gap junction protein connexin 43 (Cx43) plays a critical role in gap junction communication in rat hepatocytes. However, those located between hepatocytes are easily internalized following exposure to poisons. Herein, we investigated the potential of buffalo rat liver 3A (BRL 3A) cells to generate a...

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Detalles Bibliográficos
Autores principales: Yuan, Junzhao, Huang, Xiaoqian, Zhao, Yumeng, Gu, Jianhong, Yuan, Yan, Liu, Zongping, Zou, Hui, Bian, Jianchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778680/
https://www.ncbi.nlm.nih.gov/pubmed/36555247
http://dx.doi.org/10.3390/ijms232415607