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Metformin Attenuates Inflammation and Fibrosis in Thyroid-Associated Ophthalmopathy

The pathogenesis of thyroid-associated ophthalmopathy (TAO) is still unclear, and therapeutic drugs have great limitations. As metformin has multiple therapeutic effects in many autoimmune diseases, we explored the effects of metformin on TAO in an in vitro fibroblast model. We used orbital connecti...

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Detalles Bibliográficos
Autores principales: Xu, Zhihui, Ye, Huijing, Xiao, Wei, Sun, Anqi, Yang, Shenglan, Zhang, Te, Sha, Xiaotong, Yang, Huasheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778898/
https://www.ncbi.nlm.nih.gov/pubmed/36555150
http://dx.doi.org/10.3390/ijms232415508