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TRIB3 Mediates Fibroblast Activation and Fibrosis though Interaction with ATF4 in IPF

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by fibroblast activation, excessive deposition of extracellular matrix, and progressive scarring; the pathogenesis remains elusive. The present study explored the role of Tribbles pseudokinase 3 (TRIB3), a well-kn...

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Detalles Bibliográficos
Autores principales: Wang, Lan, Zhao, Wenyu, Xia, Cong, Li, Zhongzheng, Zhao, Weiming, Xu, Kai, Wang, Ningdan, Lian, Hui, Rosas, Ivan O., Yu, Guoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778945/
https://www.ncbi.nlm.nih.gov/pubmed/36555349
http://dx.doi.org/10.3390/ijms232415705