Cargando…

TRIB3 Mediates Fibroblast Activation and Fibrosis though Interaction with ATF4 in IPF

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by fibroblast activation, excessive deposition of extracellular matrix, and progressive scarring; the pathogenesis remains elusive. The present study explored the role of Tribbles pseudokinase 3 (TRIB3), a well-kn...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Lan, Zhao, Wenyu, Xia, Cong, Li, Zhongzheng, Zhao, Weiming, Xu, Kai, Wang, Ningdan, Lian, Hui, Rosas, Ivan O., Yu, Guoying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778945/ https://www.ncbi.nlm.nih.gov/pubmed/36555349 http://dx.doi.org/10.3390/ijms232415705

Ejemplares similares

Fenbendazole Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice via Suppression of Fibroblast-to-Myofibroblast Differentiation
por: Wang, Lan, et al.
Publicado: (2022)

Endothelial cell-derived MMP19 promotes pulmonary fibrosis by inducing E(nd)MT and monocyte infiltration
por: Zhao, Weiming, et al.
Publicado: (2023)

Injured Endothelial Cell: A Risk Factor for Pulmonary Fibrosis
por: Zhao, Weiming, et al.
Publicado: (2023)

IPF - Idiopathic Pulmonary Fibrosis
Publicado: (2019)

ADRB2 inhibition combined with antioxidant treatment alleviates lung fibrosis by attenuating TGFβ/SMAD signaling in lung fibroblasts
por: Wan, Ruyan, et al.
Publicado: (2023)

Inhibition of MAD2L1 Mediates Pulmonary Fibrosis through Impairment of Mitochondrial Function and Induction of Cell Senescence
por: Wang, Lan, et al.
Publicado: (2022)

Idiopathic Pulmonary Fibrosis (IPF): An Overview
por: Barratt, Shaney L., et al.
Publicado: (2018)

Epigenetic regulation of IPF fibroblast phenotype by glutaminolysis
por: Xiang, Zheyi, et al.
Publicado: (2022)

Single-Cell RNA Sequencing Provides New Insights into Therapeutic Roles of Thyroid Hormone in Idiopathic Pulmonary Fibrosis
por: Wang, Lan, et al.
Publicado: (2023)

Intensive Glucose Control Reduces the Risk Effect of TRIB3, SMARCD3, and ATF6 Genetic Variation on Diabetic Vascular Complications
por: He, Fazhong, et al.
Publicado: (2018)

Pharmacological or TRIB3-Mediated Suppression of ATF4 Transcriptional Activity Promotes Hepatoma Cell Resistance to Proteasome Inhibitor Bortezomib
por: Örd, Tiit, et al.
Publicado: (2021)

Interested, Though Not Competing
por: Snell, A. Saxon
Publicado: (1912)

Fibroblast paracrine TNF-α signaling elevates integrin A5 expression in idiopathic pulmonary fibrosis (IPF)
por: Epstein Shochet, Gali, et al.
Publicado: (2017)

The Potential Effects of Curcumin on Pulmonary Fibroblasts of Idiopathic Pulmonary Fibrosis (IPF)—Approaching with Next-Generation Sequencing and Bioinformatics
por: Chang, Wei-An, et al.
Publicado: (2020)

Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts
por: Schuliga, Michael, et al.
Publicado: (2018)

Artificial neural network identified the significant genes to distinguish Idiopathic pulmonary fibrosis
por: Li, Zhongzheng, et al.
Publicado: (2023)

Acute exacerbations of COPD versus IPF in patients with combined pulmonary fibrosis and emphysema
por: Zantah, Massa, et al.
Publicado: (2020)

mTORC1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in IPF fibroblasts
por: Romero, Yair, et al.
Publicado: (2016)

αAzithromycin has enhanced effects on lung fibroblasts from idiopathic pulmonary fibrosis (IPF) patients compared to controls
por: Krempaska, Kristina, et al.
Publicado: (2020)

Correction to: Azithromycin has enhanced effects on lung fibroblasts from idiopathic pulmonary fibrosis (IPF) patients compared to controls
por: Krempaska, Kristina, et al.
Publicado: (2020)

How to Be Happy Though Human
Publicado: (1957)

An Unpleasant Though Interesting Experience
por: Brown, Jno. E.
Publicado: (1896)

The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson’s disease
por: Aimé, Pascaline, et al.
Publicado: (2020)

Colitis Associated with Nintedanib Therapy for Idiopathic Pulmonary Fibrosis (IPF)
por: Oda, Keishi, et al.
Publicado: (2017)

Readily accessible CT scoring method to quantify fibrosis in IPF
por: Fraser, Emily, et al.
Publicado: (2020)

Time to diagnosis of idiopathic pulmonary fibrosis in the IPF-PRO Registry
por: Snyder, Laurie D, et al.
Publicado: (2020)

MiR-608 overexpression in idiopathic pulmonary fibrosis (IPF)
por: Epstein Shochet, Gali, et al.
Publicado: (2021)

The Effects of Epigallocatechin Gallate (EGCG) on Pulmonary Fibroblasts of Idiopathic Pulmonary Fibrosis (IPF)—A Next-Generation Sequencing and Bioinformatic Approach
por: Tsai, Ming-Ju, et al.
Publicado: (2019)

Efficacy of antifibrotic drugs, nintedanib and pirfenidone, in treatment of progressive pulmonary fibrosis in both idiopathic pulmonary fibrosis (IPF) and non-IPF: a systematic review and meta-analysis
por: Finnerty, James Patrick, et al.
Publicado: (2021)

Demographics and survival of patients with idiopathic pulmonary fibrosis in the FinnishIPF registry
por: Kaunisto, Jaana, et al.
Publicado: (2019)

Clinical characteristics of patients with familial idiopathic pulmonary fibrosis (f-IPF)
por: Krauss, Ekaterina, et al.
Publicado: (2019)

Quantitative Evaluation of Fibrosis in IPF Patients: Meaning of Diffuse Pulmonary Ossification
por: Palermo, Monica, et al.
Publicado: (2021)

Though Lost to Sight, to Memory Dear
por: Jenkyns, Ruthven
Publicado: (1882)

TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling
por: Epstein Shochet, Gali, et al.
Publicado: (2020)

Development of the ATAQ-IPF: a tool to assess quality of life in IPF
por: Swigris, Jeffrey J, et al.
Publicado: (2010)

The transition from normal lung anatomy to minimal and established fibrosis in idiopathic pulmonary fibrosis (IPF)
por: Xu, Feng, et al.
Publicado: (2021)

Management and attitudes about IPF (Idiopathic Pulmonary Fibrosis) among physicians from Latin America
por: Cherrez-Ojeda, Iván, et al.
Publicado: (2018)

Genome-wide DNA methylation dynamics in carbon tetrachloride-induced mice liver fibrosis
por: Li, Deming, et al.
Publicado: (2023)

Recommendations on treatment for IPF
por: Behr, Jürgen, et al.
Publicado: (2013)

Medical Research Council dyspnea scale does not relate to fibroblast foci profusion in IPF
por: Triantafillidou, Christina, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_tqks47arbjqfpj5e3f5pn46s6t