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5′-Chalcogen-Substituted Nucleoside Pyrophosphate and Phosphate Monoester Analogues: Preparation and Hydrolysis Studies

Novel sulfur and selenium substituted 5′,5′-linked dinucleoside pyrophate analogues were prepared in a vibration ball mill from the corresponding persilylated monophosphate. The chemical hydrolysis of pyrophosphorochalcogenolate-linked dimers was studied over a wide pH-range. The effect of the chalc...

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Detalles Bibliográficos
Autores principales: Mikkola, Satu, Eguaogie, Olga, Nieminen, Anu, Conlon, Patrick F., Jakeman, David L., Moore, Keith, Lane, Ian C., Vyle, Joseph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778984/
https://www.ncbi.nlm.nih.gov/pubmed/36555224
http://dx.doi.org/10.3390/ijms232415582