High-Yield Production of Chimeric Hepatitis E Virus-Like Particles Bearing the M2e Influenza Epitope and Receptor Binding Domain of SARS-CoV-2 in Plants Using Viral Vectors

Capsid protein of Hepatitis E virus (HEV) is capable of self-assembly into virus-like particles (VLPs) when expressed in Nicotiana benthamiana plants. Such VLPs could be used as carriers of antigens for vaccine development. In this study, we obtained VLPs based on truncated coat protein of HEV beari...

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Detalles Bibliográficos
Autores principales: Mardanova, Eugenia S., Kotlyarov, Roman Y., Stuchinskaya, Maya D., Nikolaeva, Lyudmila I., Zahmanova, Gergana, Ravin, Nikolai V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779006/
https://www.ncbi.nlm.nih.gov/pubmed/36555326
http://dx.doi.org/10.3390/ijms232415684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779006/
https://www.ncbi.nlm.nih.gov/pubmed/36555326
http://dx.doi.org/10.3390/ijms232415684

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