Clinical Impact of Next-Generation Sequencing Multi-Gene Panel Highlighting the Landscape of Germline Alterations in Ovarian Cancer Patients

BRCA1 and BRCA2 are the most frequently mutated genes in ovarian cancer (OC) crucial both for the identification of cancer predisposition and therapeutic choices. However, germline variants in other genes could be involved in OC susceptibility. We characterized OC patients to detect mutations in gen...

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Detalles Bibliográficos
Autores principales: Gurioli, Giorgia, Tedaldi, Gianluca, Farolfi, Alberto, Petracci, Elisabetta, Casanova, Claudia, Comerci, Giuseppe, Danesi, Rita, Arcangeli, Valentina, Ravegnani, Mila, Calistri, Daniele, Zampiga, Valentina, Cangini, Ilaria, Fonzi, Eugenio, Virga, Alessandra, Tassinari, Davide, Rosati, Marta, Ulivi, Paola, De Giorgi, Ugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779064/
https://www.ncbi.nlm.nih.gov/pubmed/36555431
http://dx.doi.org/10.3390/ijms232415789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779064/
https://www.ncbi.nlm.nih.gov/pubmed/36555431
http://dx.doi.org/10.3390/ijms232415789

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