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Lhb(−/−)Lhr(−/−) Double Mutant Mice Phenocopy Lhb(−/−) or Lhr(−/−) Single Mutants and Display Defects in Leydig Cells and Steroidogenesis

In the mouse, two distinct populations of Leydig cells arise during testis development. Fetal Leydig cells arise from a stem cell population and produce T required for masculinization. It is debated whether they persist in the adult testis. A second adult Leydig stem cell population gives rise to pr...

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Detalles Bibliográficos
Autores principales: Liu, Zhenghui, Larsen, Mark, Lei, Zhenmin, Rao, C. V., Kumar, T. Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779075/
https://www.ncbi.nlm.nih.gov/pubmed/36555365
http://dx.doi.org/10.3390/ijms232415725