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Lhb(−/−)Lhr(−/−) Double Mutant Mice Phenocopy Lhb(−/−) or Lhr(−/−) Single Mutants and Display Defects in Leydig Cells and Steroidogenesis
In the mouse, two distinct populations of Leydig cells arise during testis development. Fetal Leydig cells arise from a stem cell population and produce T required for masculinization. It is debated whether they persist in the adult testis. A second adult Leydig stem cell population gives rise to pr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779075/ https://www.ncbi.nlm.nih.gov/pubmed/36555365 http://dx.doi.org/10.3390/ijms232415725 |