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Targeted Methylation Profiling of Single Laser-Capture Microdissected Post-Mortem Brain Cells by Adapted Limiting Dilution Bisulfite Pyrosequencing (LDBSP)

A reoccurring issue in neuroepigenomic studies, especially in the context of neurodegenerative disease, is the use of (heterogeneous) bulk tissue, which generates noise during epigenetic profiling. A workable solution to this issue is to quantify epigenetic patterns in individually isolated neuronal...

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Detalles Bibliográficos
Autores principales: Riemens, Renzo J. M., Kenis, Gunter, Nolz, Jennifer, Susano Chaves, Sonia C., Duroux, Diane, Pishva, Ehsan, Mastroeni, Diego, Van Steen, Kristel, Haaf, Thomas, van den Hove, Daniël L. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779089/
https://www.ncbi.nlm.nih.gov/pubmed/36555213
http://dx.doi.org/10.3390/ijms232415571