Immunomodulation of HDAC Inhibitor Entinostat Potentiates the Anticancer Effects of Radiation and PD-1 Blockade in the Murine Lewis Lung Carcinoma Model

Although the combination of radiotherapy and immunotherapy has proven to be effective in lung cancer treatment, it may not be sufficient to fully activate the antitumor immune response. Here, we investigated whether entinostat, a histone deacetylase inhibitor, could improve the efficacy of radiother...

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Detalles Bibliográficos
Autores principales: Kim, Yeeun, Park, Kyunghee, Kim, Yeon Jeong, Shin, Sung-Won, Kim, Yeon Joo, Choi, Changhoon, Noh, Jae Myoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779092/
https://www.ncbi.nlm.nih.gov/pubmed/36555180
http://dx.doi.org/10.3390/ijms232415539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779092/
https://www.ncbi.nlm.nih.gov/pubmed/36555180
http://dx.doi.org/10.3390/ijms232415539

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