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Structural Change from Nonparallel to Parallel G-Quadruplex Structures in Live Cancer Cells Detected in the Lysosomes Using Fluorescence Lifetime Imaging Microscopy

Time-gated fluorescence lifetime imaging microscopy with the o-BMVC fluorescent probe provides a visualizing method for the study of exogenous G-quadruplexes (G4s) in live cancer cells. Previously, imaging results showed that the parallel G4s are accumulated and that nonparallel G4s are not detected...

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Detalles Bibliográficos
Autores principales: Tseng, Ting-Yuan, Wang, Chiung-Lin, Chang, Ta-Chau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779097/
https://www.ncbi.nlm.nih.gov/pubmed/36555440
http://dx.doi.org/10.3390/ijms232415799