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TRIAC Treatment Improves Impaired Brain Network Function and White Matter Loss in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice

Dysfunctions of the thyroid hormone (TH) transporting monocarboxylate transporter MCT8 lead to a complex X-linked syndrome with abnormal serum TH concentrations and prominent neuropsychiatric symptoms (Allan-Herndon-Dudley syndrome, AHDS). The key features of AHDS are replicated in double knockout m...

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Detalles Bibliográficos
Autores principales: Reinwald, Jonathan Rochus, Weber-Fahr, Wolfgang, Cosa-Linan, Alejandro, Becker, Robert, Sack, Markus, Falfan-Melgoza, Claudia, Gass, Natalia, Braun, Urs, Clemm von Hohenberg, Christian, Chen, Jiesi, Mayerl, Steffen, Muente, Thomas F., Heuer, Heike, Sartorius, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779161/
https://www.ncbi.nlm.nih.gov/pubmed/36555189
http://dx.doi.org/10.3390/ijms232415547