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Genetic Deletion of AT(1a) Receptor or Na(+)/H(+) Exchanger 3 Selectively in the Proximal Tubules of the Kidney Attenuates Two-Kidney, One-Clip Goldblatt Hypertension in Mice
The roles of angiotensin II (Ang II) AT(1) (AT(1a)) receptors and its downstream target Na(+)/H(+) exchanger 3 (NHE3) in the proximal tubules in the development of two-kidney, 1-clip (2K1C) Goldblatt hypertension have not been investigated previously. The present study tested the hypothesis that del...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779213/ https://www.ncbi.nlm.nih.gov/pubmed/36555438 http://dx.doi.org/10.3390/ijms232415798 |