Genetic Deletion of AT(1a) Receptor or Na(+)/H(+) Exchanger 3 Selectively in the Proximal Tubules of the Kidney Attenuates Two-Kidney, One-Clip Goldblatt Hypertension in Mice

The roles of angiotensin II (Ang II) AT(1) (AT(1a)) receptors and its downstream target Na(+)/H(+) exchanger 3 (NHE3) in the proximal tubules in the development of two-kidney, 1-clip (2K1C) Goldblatt hypertension have not been investigated previously. The present study tested the hypothesis that del...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiao Chun, Hassan, Rumana, Leite, Ana Paula O., Katsurada, Akemi, Dugas, Courtney, Sato, Ryosuke, Zhuo, Jia Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779213/
https://www.ncbi.nlm.nih.gov/pubmed/36555438
http://dx.doi.org/10.3390/ijms232415798

Ejemplares similares

Ejemplares similares