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Conserved Double Translation Initiation Site for Δ160p53 Protein Hints at Isoform’s Key Role in Mammalian Physiology

p53 is the most commonly mutated gene in human cancers. Two fundamental reasons for this are its long protein isoforms protect from cancer, while its shorter C-terminal isoforms can support cancer and metastasis. Previously, we have shown that the Δ160p53 protein isoform enhances survival and the in...

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Detalles Bibliográficos
Autores principales: López-Iniesta, Maria José, Parkar, Shrutee N., Ramalho, Ana Catarina, Lacerda, Rafaela, Costa, Inês F., Zhao, Jingyuan, Romão, Luísa, Candeias, Marco M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779343/
https://www.ncbi.nlm.nih.gov/pubmed/36555484
http://dx.doi.org/10.3390/ijms232415844