Klotho Protein Decreases MMP-Mediated Degradation of Contractile Proteins during Ischaemia/Reperfusion Injury to the Cardiomyocytes

Ischaemia, followed by reperfusion, causes the generation of reactive oxygen species, overproduction of peroxynitrite, activation of matrix metalloproteinases (MMPs), and subsequently the degradation of heart contractile proteins in the cardiomyocytes. Klotho is a membrane-bound or soluble protein t...

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Detalles Bibliográficos
Autores principales: Olejnik, Agnieszka, Krzywonos-Zawadzka, Anna, Banaszkiewicz, Marta, Bil-Lula, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779408/
https://www.ncbi.nlm.nih.gov/pubmed/36555091
http://dx.doi.org/10.3390/ijms232415450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779408/
https://www.ncbi.nlm.nih.gov/pubmed/36555091
http://dx.doi.org/10.3390/ijms232415450

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