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Heterologous Expression Reveals Ancient Properties of Tei3—A VanS Ortholog from the Teicoplanin Producer Actinoplanes teichomyceticus

Glycopeptide antibiotics (GPAs) are among the most clinically successful antimicrobials. GPAs inhibit cell-wall biosynthesis in Gram-positive bacteria via binding to lipid II. Natural GPAs are produced by various actinobacteria. Being themselves Gram-positives, the GPA producers evolved sophisticate...

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Detalles Bibliográficos
Autores principales: Yushchuk, Oleksandr, Zhukrovska, Kseniia, Ostash, Bohdan, Fedorenko, Victor, Marinelli, Flavia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779433/
https://www.ncbi.nlm.nih.gov/pubmed/36555354
http://dx.doi.org/10.3390/ijms232415713