The Educational Program of Macrophages toward a Hyperprogressive Disease-Related Phenotype Is Orchestrated by Tumor-Derived Extracellular Vesicles

Hyperprogressive disease (HPD), an aggressive acceleration of tumor growth, was observed in a group of cancer patients treated with anti-PD1/PDL1 antibodies. The presence of a peculiar macrophage subset in the tumor microenvironment is reported to be a sort of “immunological prerequisite” for HPD de...

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Detalles Bibliográficos
Autores principales: Indino, Serena, Borzi, Cristina, Moscheni, Claudia, Sartori, Patrizia, De Cecco, Loris, Bernardo, Giancarla, Le Noci, Valentino, Arnaboldi, Francesca, Triulzi, Tiziana, Sozzi, Gabriella, Tagliabue, Elda, Sfondrini, Lucia, Gagliano, Nicoletta, Moro, Massimo, Sommariva, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779478/
https://www.ncbi.nlm.nih.gov/pubmed/36555441
http://dx.doi.org/10.3390/ijms232415802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779478/
https://www.ncbi.nlm.nih.gov/pubmed/36555441
http://dx.doi.org/10.3390/ijms232415802

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