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The Educational Program of Macrophages toward a Hyperprogressive Disease-Related Phenotype Is Orchestrated by Tumor-Derived Extracellular Vesicles
Hyperprogressive disease (HPD), an aggressive acceleration of tumor growth, was observed in a group of cancer patients treated with anti-PD1/PDL1 antibodies. The presence of a peculiar macrophage subset in the tumor microenvironment is reported to be a sort of “immunological prerequisite” for HPD de...
Autores principales: | Indino, Serena, Borzi, Cristina, Moscheni, Claudia, Sartori, Patrizia, De Cecco, Loris, Bernardo, Giancarla, Le Noci, Valentino, Arnaboldi, Francesca, Triulzi, Tiziana, Sozzi, Gabriella, Tagliabue, Elda, Sfondrini, Lucia, Gagliano, Nicoletta, Moro, Massimo, Sommariva, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779478/ https://www.ncbi.nlm.nih.gov/pubmed/36555441 http://dx.doi.org/10.3390/ijms232415802 |
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