Hydroxychloroquine Mitigates Dilated Cardiomyopathy Phenotype in Transgenic D94A Mice

In this study, we aimed to investigate whether short-term and low-dose treatment with hydroxychloroquine (HCQ), an antimalarial drug, can modulate heart function in a preclinical model of dilated cardiomyopathy (DCM) expressing the D94A mutation in cardiac myosin regulatory light chain (RLC) compare...

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Detalles Bibliográficos
Autores principales: Kanashiro-Takeuchi, Rosemeire M., Kazmierczak, Katarzyna, Liang, Jingsheng, Takeuchi, Lauro M., Sitbon, Yoel H., Szczesna-Cordary, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779604/
https://www.ncbi.nlm.nih.gov/pubmed/36555229
http://dx.doi.org/10.3390/ijms232415589