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Hydroxychloroquine Mitigates Dilated Cardiomyopathy Phenotype in Transgenic D94A Mice
In this study, we aimed to investigate whether short-term and low-dose treatment with hydroxychloroquine (HCQ), an antimalarial drug, can modulate heart function in a preclinical model of dilated cardiomyopathy (DCM) expressing the D94A mutation in cardiac myosin regulatory light chain (RLC) compare...
Autores principales: | Kanashiro-Takeuchi, Rosemeire M., Kazmierczak, Katarzyna, Liang, Jingsheng, Takeuchi, Lauro M., Sitbon, Yoel H., Szczesna-Cordary, Danuta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779604/ https://www.ncbi.nlm.nih.gov/pubmed/36555229 http://dx.doi.org/10.3390/ijms232415589 |
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