Single-Cell RNA Sequencing for the Detection of Clonotypic V(D)J Rearrangements in Multiple Myeloma

Multiple myeloma (MM) has a highly heterogeneous genetic background, which complicates its molecular tracking over time. Nevertheless, each MM patient’s malignant plasma cells (PCs) share unique V(D)J rearranged sequences at immunoglobulin loci, which represent ideal disease biomarkers. Because the...

Descripción completa

Detalles Bibliográficos
Autores principales: Matera, Antonio, Marella, Alessio, Maeda, Akihiro, Da Vià, Matteo C., Lazzaroni, Francesca, Fabris, Sonia, Pioggia, Stefania, Porretti, Laura, Colombo, Federico, Torricelli, Federica, Neri, Antonino, Taiana, Elisa, Fabbiano, Giuseppina, Traini, Valentina, Genuardi, Elisa, Drandi, Daniela, Bolli, Niccolò, Lionetti, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779610/
https://www.ncbi.nlm.nih.gov/pubmed/36555330
http://dx.doi.org/10.3390/ijms232415691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779610/
https://www.ncbi.nlm.nih.gov/pubmed/36555330
http://dx.doi.org/10.3390/ijms232415691

Ejemplares similares