Isogenic Human-Induced Pluripotent Stem-Cell-Derived Cardiomyocytes Reveal Activation of Wnt Signaling Pathways Underlying Intrinsic Cardiac Abnormalities in Rett Syndrome

Rett syndrome (RTT) is a severe neurodevelopmental disorder caused by MeCP2 mutations. Nonetheless, the pathophysiological roles of MeCP2 mutations in the etiology of intrinsic cardiac abnormality and sudden death remain unclear. In this study, we performed a detailed functional studies (calcium and...

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Detalles Bibliográficos
Autores principales: Ng, Kwong-Man, Ding, Qianqian, Tse, Yiu-Lam, Chou, Oscar Hou-In, Lai, Wing-Hon, Au, Ka-Wing, Lau, Yee-Man, Ji, Yue, Siu, Chung-Wah, Tang, Clara Sze-Man, Colman, Alan, Tsang, Suk-Ying, Tse, Hung-Fat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779632/
https://www.ncbi.nlm.nih.gov/pubmed/36555252
http://dx.doi.org/10.3390/ijms232415609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779632/
https://www.ncbi.nlm.nih.gov/pubmed/36555252
http://dx.doi.org/10.3390/ijms232415609

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