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A broadly neutralizing monoclonal antibody overcomes the mutational landscape of emerging SARS-CoV-2 variants of concern

The emergence of new variants of SARS-CoV-2 necessitates unremitting efforts to discover novel therapeutic monoclonal antibodies (mAbs). Here, we report an extremely potent mAb named P4A2 that can neutralize all the circulating variants of concern (VOCs) with high efficiency, including the highly tr...

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Detalles Bibliográficos
Autores principales: Parray, Hilal Ahmad, Narayanan, Naveen, Garg, Sonal, Rizvi, Zaigham Abbas, Shrivastava, Tripti, Kushwaha, Sachin, Singh, Janmejay, Murugavelu, Praveenkumar, Anantharaj, Anbalagan, Mehdi, Farha, Raj, Nisha, Singh, Shivam, Dandotiya, Jyotsna, Lukose, Asha, Jamwal, Deepti, Kumar, Sandeep, Chiranjivi, Adarsh K., Dhyani, Samridhi, Mishra, Nitesh, Kumar, Sanjeev, Jakhar, Kamini, Sonar, Sudipta, Panchal, Anil Kumar, Tripathy, Manas Ranjan, Chowdhury, Shirlie Roy, Ahmed, Shubbir, Samal, Sweety, Mani, Shailendra, Bhattacharyya, Sankar, Das, Supratik, Sinha, Subrata, Luthra, Kalpana, Batra, Gaurav, Sehgal, Devinder, Medigeshi, Guruprasad R., Sharma, Chandresh, Awasthi, Amit, Garg, Pramod Kumar, Nair, Deepak T., Kumar, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779650/
https://www.ncbi.nlm.nih.gov/pubmed/36508467
http://dx.doi.org/10.1371/journal.ppat.1010994