Cytochrome P450 2D6 (CYP2D6) and glucose-6-phosphate dehydrogenase (G6PD) genetic variations in Thai vivax malaria patients: Implications for 8-aminoquinoline radical cure

BACKGROUND: Primaquine and tafenoquine are the only licensed drugs that effectively kill the hypnozoite stage and are used to prevent Plasmodium vivax malaria relapse. However, both primaquine and tafenoquine can cause acute hemolysis in glucose-6-phosphate dehydrogenase (G6PD)-deficient people with...

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Detalles Bibliográficos
Autores principales: Chamchoy, Kamonwan, Sudsumrit, Sirapapha, Thita, Thanyapit, Krudsood, Srivicha, Patrapuvich, Rapatbhorn, Boonyuen, Usa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779666/
https://www.ncbi.nlm.nih.gov/pubmed/36508454
http://dx.doi.org/10.1371/journal.pntd.0010986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779666/
https://www.ncbi.nlm.nih.gov/pubmed/36508454
http://dx.doi.org/10.1371/journal.pntd.0010986

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