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Metabolic reprogramming in Rheumatoid Arthritis Synovial Fibroblasts: A hybrid modeling approach

Rheumatoid Arthritis (RA) is an autoimmune disease characterized by a highly invasive pannus formation consisting mainly of Synovial Fibroblasts (RASFs). This pannus leads to cartilage, bone, and soft tissue destruction in the affected joint. RASFs’ activation is associated with metabolic alteration...

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Detalles Bibliográficos
Autores principales: Aghakhani, Sahar, Soliman, Sylvain, Niarakis, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779668/
https://www.ncbi.nlm.nih.gov/pubmed/36508473
http://dx.doi.org/10.1371/journal.pcbi.1010408