Bioanalysis of Oligonucleotide by LC–MS: Effects of Ion Pairing Regents and Recent Advances in Ion-Pairing-Free Analytical Strategies

Oligonucleotides (OGNs) are relatively new modalities that offer unique opportunities to expand the therapeutic targets. Reliable and high-throughput bioanalytical methods are pivotal for preclinical and clinical investigations of therapeutic OGNs. Liquid chromatography–mass spectrometry (LC–MS) is...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Aowen, Cheng, Ming, Zhou, Yixuan, Deng, Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779676/
https://www.ncbi.nlm.nih.gov/pubmed/36555119
http://dx.doi.org/10.3390/ijms232415474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779676/
https://www.ncbi.nlm.nih.gov/pubmed/36555119
http://dx.doi.org/10.3390/ijms232415474

Ejemplares similares