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Bioanalysis of Oligonucleotide by LC–MS: Effects of Ion Pairing Regents and Recent Advances in Ion-Pairing-Free Analytical Strategies

Oligonucleotides (OGNs) are relatively new modalities that offer unique opportunities to expand the therapeutic targets. Reliable and high-throughput bioanalytical methods are pivotal for preclinical and clinical investigations of therapeutic OGNs. Liquid chromatography–mass spectrometry (LC–MS) is...

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Detalles Bibliográficos
Autores principales:	Liu, Aowen, Cheng, Ming, Zhou, Yixuan, Deng, Pan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779676/ https://www.ncbi.nlm.nih.gov/pubmed/36555119 http://dx.doi.org/10.3390/ijms232415474

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