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Glial Gap Junction Pathology in the Spinal Cord of the 5xFAD Mouse Model of Early-Onset Alzheimer’s Disease

Gap junctions (GJs) are specialized transmembrane channels assembled by two hemi-channels of six connexin (Cx) proteins that facilitate neuroglial crosstalk in the central nervous system (CNS). Previous studies confirmed the crucial role of glial GJs in neurodegenerative disorders with dementia or m...

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Detalles Bibliográficos
Autores principales: Pechlivanidou, Maria, Kousiappa, Ioanna, Angeli, Stella, Sargiannidou, Irene, Koupparis, Andreas M., Papacostas, Savvas S., Kleopa, Kleopas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779687/
https://www.ncbi.nlm.nih.gov/pubmed/36555237
http://dx.doi.org/10.3390/ijms232415597