Identification of Novel Artemisinin Hybrids Induce Apoptosis and Ferroptosis in MCF-7 Cells

A series of novel 1,3,4-oxadiazole-artemisinin hybrids have been designed and synthesized. An MTT assay revealed that most of tested hybrids showed more enhanced anti-proliferative activities than artemisinin, among which A8 had the superior potency with IC(50) values ranging from 4.07 μM to 9.71 μM...

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Detalles Bibliográficos
Autores principales: Zhong, Ye, Li, Zhi-Ning, Jiang, Xin-Yue, Tian, Xing, Deng, Ming-Hui, Cheng, Mao-Sheng, Yang, Hua-Li, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779727/
https://www.ncbi.nlm.nih.gov/pubmed/36555409
http://dx.doi.org/10.3390/ijms232415768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779727/
https://www.ncbi.nlm.nih.gov/pubmed/36555409
http://dx.doi.org/10.3390/ijms232415768

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