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Rbm20(ΔRRM) Mice, Expressing a Titin Isoform with Lower Stiffness, Are Protected from Mechanical Ventilation-Induced Diaphragm Weakness

Diaphragm weakness frequently develops in mechanically ventilated critically ill patients and is associated with increased morbidity, including ventilator weaning failure, mortality, and health care costs. The mechanisms underlying diaphragm weakness are incompletely understood but may include the e...

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Detalles Bibliográficos
Autores principales: van den Berg, Marloes, Peters, Eva L., van der Pijl, Robbert J., Shen, Shengyi, Heunks, Leo M. A., Granzier, Henk L., Ottenheijm, Coen A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779751/
https://www.ncbi.nlm.nih.gov/pubmed/36555335
http://dx.doi.org/10.3390/ijms232415689