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Rbm20(ΔRRM) Mice, Expressing a Titin Isoform with Lower Stiffness, Are Protected from Mechanical Ventilation-Induced Diaphragm Weakness
Diaphragm weakness frequently develops in mechanically ventilated critically ill patients and is associated with increased morbidity, including ventilator weaning failure, mortality, and health care costs. The mechanisms underlying diaphragm weakness are incompletely understood but may include the e...
Autores principales: | van den Berg, Marloes, Peters, Eva L., van der Pijl, Robbert J., Shen, Shengyi, Heunks, Leo M. A., Granzier, Henk L., Ottenheijm, Coen A. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779751/ https://www.ncbi.nlm.nih.gov/pubmed/36555335 http://dx.doi.org/10.3390/ijms232415689 |
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