Molecular mechanism underlying desensitization of the proton-activated chloride channel PAC

Desensitization is a common property of membrane receptors, including ion channels. The newly identified proton-activated chloride (PAC) channel plays an important role in regulating the pH and size of organelles in the endocytic pathway, and is also involved in acid-induced cell death. However, how...

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Detalles Bibliográficos
Autores principales: Osei-Owusu, James, Ruan, Zheng, Mihaljević, Ljubica, Matasic, Daniel S, Chen, Kevin Hong, Lü, Wei, Qiu, Zhaozhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779784/
https://www.ncbi.nlm.nih.gov/pubmed/36547405
http://dx.doi.org/10.7554/eLife.82955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779784/
https://www.ncbi.nlm.nih.gov/pubmed/36547405
http://dx.doi.org/10.7554/eLife.82955

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