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Cellular features of localized microenvironments in human meniscal degeneration: a single-cell transcriptomic study

BACKGROUND: Musculoskeletal tissue degeneration impairs the life quality and function of many people. Meniscus degeneration is a major origin of knee osteoarthritis and a common threat to athletic ability, but its cellular mechanism remains elusive. METHODS: We built a cell atlas of 12 healthy or de...

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Detalles Bibliográficos
Autores principales: Fu, Weili, Chen, Sijie, Yang, Runze, Li, Chen, Gao, Haoxiang, Li, Jian, Zhang, Xuegong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779791/
https://www.ncbi.nlm.nih.gov/pubmed/36548025
http://dx.doi.org/10.7554/eLife.79585