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Donor Genetic Predisposition to High Interleukin-10 Production Appears Protective against Acute Graft-Versus-Host Disease

The persistence of graft-versus-host disease (GVHD) as the principal complication of allogeneic hematopoietic cell transplantation (HCT) demonstrates that HLA matching alone is insufficient to prevent alloreactivity. We performed molecular and functional characterization of 22 candidate cytokine gen...

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Detalles Bibliográficos
Autores principales: Tripathi, Gaurav, Khanolkar, Rutvij A., Faridi, Rehan M., Kalra, Amit, Dharmani-Khan, Poonam, Shabani-Rad, Meer-Taher, Berka, Noureddine, Daly, Andrew, Storek, Jan, Khan, Faisal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779827/
https://www.ncbi.nlm.nih.gov/pubmed/36555525
http://dx.doi.org/10.3390/ijms232415888