Attenuation of Smooth Muscle Cell Phenotypic Switching by Angiotensin 1-7 Protects against Thoracic Aortic Aneurysm

Thoracic aortic aneurysm (TAA) involves extracellular matrix (ECM) remodeling of the aortic wall, leading to reduced biomechanical support with risk of aortic dissection and rupture. Activation of the renin-angiotensin system, and resultant angiotensin (Ang) II synthesis, is critically involved in t...

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Detalles Bibliográficos
Autores principales: Jadli, Anshul S., Ballasy, Noura N., Gomes, Karina P., Mackay, Cameron D. A., Meechem, Megan, Wijesuriya, Tishani Methsala, Belke, Darrell, Thompson, Jennifer, Fedak, Paul W. M., Patel, Vaibhav B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779869/
https://www.ncbi.nlm.nih.gov/pubmed/36555207
http://dx.doi.org/10.3390/ijms232415566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779869/
https://www.ncbi.nlm.nih.gov/pubmed/36555207
http://dx.doi.org/10.3390/ijms232415566

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