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Attenuation of Smooth Muscle Cell Phenotypic Switching by Angiotensin 1-7 Protects against Thoracic Aortic Aneurysm
Thoracic aortic aneurysm (TAA) involves extracellular matrix (ECM) remodeling of the aortic wall, leading to reduced biomechanical support with risk of aortic dissection and rupture. Activation of the renin-angiotensin system, and resultant angiotensin (Ang) II synthesis, is critically involved in t...
Autores principales: | Jadli, Anshul S., Ballasy, Noura N., Gomes, Karina P., Mackay, Cameron D. A., Meechem, Megan, Wijesuriya, Tishani Methsala, Belke, Darrell, Thompson, Jennifer, Fedak, Paul W. M., Patel, Vaibhav B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779869/ https://www.ncbi.nlm.nih.gov/pubmed/36555207 http://dx.doi.org/10.3390/ijms232415566 |
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