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miRNA nanoencapsulation to regulate the programming of the blood-brain barrier permeability by hypoxia
Central nervous system (CNS)-related diseases are difficult to treat as most therapeutic agents they cannot reach the brain tissue, mainly due to the blood-brain barrier (BBB), arguably the tightest barrier between the human body and cerebral parenchyma, which routinely excludes most xenobiotic ther...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780061/ https://www.ncbi.nlm.nih.gov/pubmed/36568262 http://dx.doi.org/10.1016/j.crphar.2022.100129 |