A statistical framework for high-content phenotypic profiling using cellular feature distributions

High-content screening (HCS) uses microscopy images to generate phenotypic profiles of cell morphological data in high-dimensional feature space. While HCS provides detailed cytological information at single-cell resolution, these complex datasets are usually aggregated into summary statistics that...

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Detalles Bibliográficos
Autores principales: Pearson, Yanthe E., Kremb, Stephan, Butterfoss, Glenn L., Xie, Xin, Fahs, Hala, Gunsalus, Kristin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780213/
https://www.ncbi.nlm.nih.gov/pubmed/36550289
http://dx.doi.org/10.1038/s42003-022-04343-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780213/
https://www.ncbi.nlm.nih.gov/pubmed/36550289
http://dx.doi.org/10.1038/s42003-022-04343-3

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