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A statistical framework for high-content phenotypic profiling using cellular feature distributions
High-content screening (HCS) uses microscopy images to generate phenotypic profiles of cell morphological data in high-dimensional feature space. While HCS provides detailed cytological information at single-cell resolution, these complex datasets are usually aggregated into summary statistics that...
Autores principales: | Pearson, Yanthe E., Kremb, Stephan, Butterfoss, Glenn L., Xie, Xin, Fahs, Hala, Gunsalus, Kristin C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780213/ https://www.ncbi.nlm.nih.gov/pubmed/36550289 http://dx.doi.org/10.1038/s42003-022-04343-3 |
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