Fibroblast growth factor-2 bound to specific dermal fibroblast-derived extracellular vesicles is protected from degradation

Fibroblast growth factor-2 (FGF2) has multiple roles in cutaneous wound healing but its natural low stability prevents the development of its use in skin repair therapies. Here we show that FGF2 binds the outer surface of dermal fibroblast (DF)-derived extracellular vesicles (EVs) and this associati...

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Detalles Bibliográficos
Autores principales: Petit, Isabelle, Levy, Ayelet, Estrach, Soline, Féral, Chloé C., Trentin, Andrea Gonçalves, Dingli, Florent, Loew, Damarys, Qu, Jieqiong, Zhou, Huiqing, Théry, Clotilde, Prunier, Céline, Aberdam, Daniel, Ferrigno, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780220/
https://www.ncbi.nlm.nih.gov/pubmed/36550142
http://dx.doi.org/10.1038/s41598-022-26217-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780220/
https://www.ncbi.nlm.nih.gov/pubmed/36550142
http://dx.doi.org/10.1038/s41598-022-26217-8

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