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Fibroblast growth factor-2 bound to specific dermal fibroblast-derived extracellular vesicles is protected from degradation
Fibroblast growth factor-2 (FGF2) has multiple roles in cutaneous wound healing but its natural low stability prevents the development of its use in skin repair therapies. Here we show that FGF2 binds the outer surface of dermal fibroblast (DF)-derived extracellular vesicles (EVs) and this associati...
Autores principales: | Petit, Isabelle, Levy, Ayelet, Estrach, Soline, Féral, Chloé C., Trentin, Andrea Gonçalves, Dingli, Florent, Loew, Damarys, Qu, Jieqiong, Zhou, Huiqing, Théry, Clotilde, Prunier, Céline, Aberdam, Daniel, Ferrigno, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780220/ https://www.ncbi.nlm.nih.gov/pubmed/36550142 http://dx.doi.org/10.1038/s41598-022-26217-8 |
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