Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2

Originally discovered in the circulation of pregnant women as a protein secreted by placental trophoblasts, the metalloprotease pregnancy-associated plasma protein A (PAPP-A) is also widely expressed by many other tissues. It cleaves insulin-like growth factor-binding proteins (IGFBPs) to increase t...

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Detalles Bibliográficos
Autores principales: Zhong, Qihang, Chu, Honglei, Wang, Guopeng, Zhang, Cheng, Li, Rong, Guo, Fusheng, Meng, Xinlu, Lei, Xiaoguang, Zhou, Youli, Ren, Ruobing, Tao, Lin, Li, Ningning, Gao, Ning, Wei, Yuan, Qiao, Jie, Hang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780223/
https://www.ncbi.nlm.nih.gov/pubmed/36550107
http://dx.doi.org/10.1038/s41421-022-00502-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780223/
https://www.ncbi.nlm.nih.gov/pubmed/36550107
http://dx.doi.org/10.1038/s41421-022-00502-2

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