ERK/mTOR signaling may underlying the antidepressant actions of rapastinel in mice

Rapastinel as the allosteric modulator of N-methyl-D-aspartate receptor (NMDAR) produces rapid antidepressant-like effects dependent on brain-derived neurotrophic factor (BDNF) and VGF (nonacryonimic) release. Herein, we further explore the molecular mechanisms of the antidepressant effects of repea...

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Detalles Bibliográficos
Autores principales: Shen, Mengxin, Lv, Dan, Liu, Xinya, Wang, Chuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780240/
https://www.ncbi.nlm.nih.gov/pubmed/36550125
http://dx.doi.org/10.1038/s41398-022-02290-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780240/
https://www.ncbi.nlm.nih.gov/pubmed/36550125
http://dx.doi.org/10.1038/s41398-022-02290-5

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