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Astrocytes amplify neurovascular coupling to sustained activation of neocortex in awake mice

Functional hyperemia occurs when enhanced neuronal activity signals to increase local cerebral blood flow (CBF) to satisfy regional energy demand. Ca(2+) elevation in astrocytes can drive arteriole dilation to increase CBF, yet affirmative evidence for the necessity of astrocytes in functional hyper...

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Detalles Bibliográficos
Autores principales: Institoris, Adam, Vandal, Milène, Peringod, Govind, Catalano, Christy, Tran, Cam Ha, Yu, Xinzhu, Visser, Frank, Breiteneder, Cheryl, Molina, Leonardo, Khakh, Baljit S., Nguyen, Minh Dang, Thompson, Roger J., Gordon, Grant R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780254/
https://www.ncbi.nlm.nih.gov/pubmed/36550102
http://dx.doi.org/10.1038/s41467-022-35383-2